Our hypothesis is that the molecular clock in skeletal muscle cells is responsive to mechanical stimuli and that this mechanism is mediated by lamins through nuclear tethering of clock transcription factors.…

In my project I am investigating the regulation and crosstalk between chromatin and selective autophagy and the role of INO80 in this.…

As part of my Unilever-sponsored CASE project, I am conducting an in vitro investigation into the activity of Orai channels in skin cell lines.…

Reactive oxygen species (ROS) arise through normal cell metabolism or from the environment. Hence, it is important for lifelong health and wellbeing to understand the mechanisms by which cells respond to ROS.…

Mitochondrial dysfunction is associated with several neurodegenerative and muscular diseases and ageing.…